The Lazio duo have been in fine form but may not start at Celtic Park.
The report states that Immobile is likely to be named on the bench with Ecuadorian striker Felipe Caicedo set to be selected instead.
Alberto meanwhile is said to be nursing a knock in the wake of Lazio’s 3-3 draw with Atalanta at the weekend and is unlikely to feature at all.
The paper believe that the Italians could make as many as six changes for the group stage match, citing Italian media sources.
The absence of the Immobile and Alberto would represent a big boost to Celtic’s chances of winning given their excellent form so far this season.
The Italian striker has scored an impressive 10 goals in just nine appearances this season, also creating three assists. No-one in Serie A has netted more than him so far this term.
Alberto is also proving to be one of the most creative players in Italy, registering six assists and goal in nine matches. Again, nobody has more assists than him in the Italian top-flight this season.
While Lazio have plenty of talent readily available that can punish Celtic, does rotation suggest this competition is less important to them than the Hoops?
Neil Lennon is set to name his strongest possible side and as witness against Cluj, the Hoops are hungry to make an impact on the Europa League.
In front of a sold-out Celtic Park it’s set to be a fascinating evening.
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