Tottenham got the better of City 2-0 at Tottenham Hotspur Stadium in the Premier League on Saturday evening.
Midfielder Ndombele provided the assist for the first goal, while striker Kane was the architect of the second.
Both the players worked hard, with Kane dropping deep and making it tough for City.
City manager Guardiola has outlined the role Kane and Ndombele played in the win for Spurs.
Guardiola told Football.London about Kane: “It’s my fifth season here so I was able to see him so many times. An exceptional player and everybody knows it.”
The Spaniard told BBC Sport: “We knew before the game that you cannot give them the first goal. We had more chances and them but we lost. Mourinho’s teams are like this, you make a mistake and they punish you on the counter attack.
“It is not easy. Harry Kane and Ndombele are on halfway, the space is so difficult, our possession play was good, but football is the boxes and that is where we were not good.”
According to WhoScored, against City on Saturday evening, Kane played one key pass, had a pass accuracy of 64.3%, took 48 touches, and made three tackles and one clearance.
Ndombele played one key pass, had a pass accuracy of 78.3%, took 30 touches, and made two tackles and one interception, according to WhoScored.
Kane did not score, but he was a problem for the City defence and provided an extra body in midfield when he had to.
As for Ndombele, the France international midfielder was brilliant in midfield and worked tremendously hard, as he closed down space and made it tough for the opposition.