Mauricio Pochettino's charges travelled to Belgrade to face Red Star and got the job done in style as Giovani Lo Celso opened the scoring on his first start for Tottenham, before Son Heung-min struck a brace and Christian Eriksen added a fourth late on.
Although Ndombele and Kane did not score, the former put in a solid display in central midfield, pushing forward with the ball at every opportunity and showing lots of great skill, while the latter had several opportunities to get on the scoresheet, and also played a role in Son's second goal with a great ball for Danny Rose.
"I think the most important thing tonight is the result for Spurs - to come away with four goals, seeing new players and amount of possession that they had," Brown told BBC Sport at full time. "I was impressed with Ndombele and Kane who looked hungry in the first half to make things happen. It was a good away performance at a tricky place."
Tottenham now sit second in Group B, four points clear of Red Star in third, knowing one victory from their final two games will ensure progression to the last 16.
Up next for Spurs in the Champions League is Olympiacos at the Tottenham Hotspur Stadium on 26 November, while Sheffield United head to North London this weekend in the Premier League.
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