The Everton manager could do with a win to ease pressure on his shoulders.
The full match squad is as follows:
Starting XI - Pickford, Coleman, Holgate, Mina, Digne, Delph, Andre Gomes, Kean, Iwobi, Richarlison, Calvert-Lewin.
Substitutes - Lossl, Keane, Sigurdsson, Walcott, Tosun, Sidibe, Davies.
The Toffees' recent win over West Ham threatened to see them turn a corner on poor form this season, but a failure to follow that up against Brighton at the weekend has ensured there's again a bit of pressure on Silva's team to deliver tonight.
Everton have won just two of their last seven matches, with one of those coming in this competition against Sheffield Wednesday.
The quarter-finals are now in sight and there's a sense that this could be a chance for Silva and his team to win silverware.
No surprise then to see Silva name a strong side. A number of regular starters feature, unlike others in the tournament who often choose to fill their eleven up with youngsters and untested talent.
The selection of big summer signing Moise Kean is the headline news, having not started since September.
Richarlison, Alex Iwobi and Kean will be hoping to provide a potent attacking threat in support of Dominic Calvert-Lewin, who has five goals to his name this season.
History is in the home side's favour tonight. Watford have never won a match at Goodison Park, losing 12 of their 14 matches at the venue.
As mentioned, Everton's recent form is poor, but it's not as if the Hornets are in exceptional mood either. They are now winless in their last four, scoring just one goal in that time.
With the home advantage, Silva's team should progress.
Can they rise to the challenge?
Have something to tell us about this article?