Tottenham Hotspur starting XI: Lloris; Trippier, Sanchez, Alderweireld, Vertonghen; Wanyama, Eriksen, Rose, Alli; Llorente, Moura.
Tottenham Hotspur substitutes: Gazzaniga, Foyth, Walker-Peters, Davies, Dier, Skipp, Sissoko.
Ajax starting XI: Onana; Veltman, De Ligt, Blind, Tagliafico; De Jong, Van de Beek; Neres, Ziyech, Schone; Tadic.
Ajax substitutes: Varela, Sinkgraven, Huntelaar, Mazraoui, Magallan, Dolberg, De Wit.
Spurs head into the game after defeat to West Ham United on Saturday, and will be missing the injured Harry Kane and suspended Son Heung-min.
Hugo Lloris starts in goal tonight, behind what is being presented as a back four of Kieran Trippier, Davinson Sanchez, Toby Alderweireld and Jan Vertonghen, with the latter three all ex-Ajax players.
Danny Rose appears to be playing in midfield, alongside Victor Wanyama and Christian Eriksen, with Dele Alli supporting Fernando Llorente and Lucas Moura up top.
Moussa Sissoko is back from injury to start on the bench, alongside Paulo Gazzaniga, Juan Foyth, Kyle Walker-Peters, Ben Davies, Eric Dier and Oliver Skipp.
Meanwhile, Ajax go with Andre Onana in goal, behind a back four of Joel Veltman, Matthijs De Ligt, Daley Blind and Nicolas Tagliafico.
Frenkie de Jong starts with Donny van de Beek in midfield, with Hakim Ziyech, David Neres and Lasse Schone featuring behind striker Dusan Tadic.
Bruno Varela, Daley Sinkgraven, Klaas-Jan Huntelaar, Noussair Mazraoui, Lisandro Magallan, Kasper Dolberg and Dani de Wit make up the Ajax bench tonight.
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