Tottenham visit Manchester City this evening in the Champions League.
Tottenham Hotspur take on Manchester City this evening in the Champions League quarter-finals at The Etihad,
Spurs have a 1-0 lead and will be determined to protect their advantage.
This is why it is likely Tottenham will continue to play three at the back as they did at the weekend, and in the first leg.
Spurs also did so against Borussia Dortmund with success in the previous round.
Tottenham's three best central defenders, Toby Alderweireld, Jan Vertonghen and Davinson Sanchez are most likely to get the nod, even though Ben Davies featured in the first leg.
Serge Aurier's injury means Kieran Trippier at right wing-back, and Danny Rose's attacking qualities should give him the nod on the left as Spurs look to kill off the game on the counter attack.
An injury to Harry Winks makes Tottenham's central midfield pairing of Moussa Sissoko and Victor Wanyama likely.
In the attacking positions it is harder to assess Mauricio Pochettino's plans.
He must select three of Lucas Moura, Heung Min Son, Fernando Llorente, Dele Alli and Christian Eriksen.
With £25 million star Lucas scoring a hat-trick at the weekend, he should get the nod up front ahead of Llorente, while means Eriksen and Son would get the remaining spots.
Alli is suffering a hand injury and should be used from the bench, which is likely considering Son was rested at the weekend for this fixture.
How do you think Spurs will line up?