Spurs overcame Borussia Dortmund in the last 16 by a 4-0 aggregate scoreline, a 3-0 hammering of the Bundesliga side at Wembley followed up by a professional 1-0 win at the Signal Iduna Park.
However, Friday's draw against the Premier League leaders prompted a fair bit of pessimistic reaction on Twitter, with some Tottenham fans suggesting that their Champions League journey would end at the hands of Pep Guardiola's side.
Speaking to the official Spurs website, Kane described the Citizens as "one of the best teams in Europe" but despite admitting that it'll be a tough task, he says he and his teammates believe they can get the job done.
“They’re going to be two great games,” he said. “Manchester City are obviously one of the best teams in Europe at the moment so it will be a great test for us. In the quarter-finals of the Champions League you have to expect to play tough teams though, so we will be ready for it.”
When asked about whether he thinks they can beat City over two legs, he replied: “Yes. We have to believe in our ability. It will be tough but it’s a chance to get to a Champions League semi-final so we will give it everything.”
Some Spurs fans had their say on their 24-goal talisman's comments on Twitter, with reaction pretty much split down the middle between optimism and pessimism:
Just like we supposedly gave everything v Southampton— 40winks__ (@SpursTransfer10) March 16, 2019
Put in an actual performance (not just you harry , the other boys as well).
Let's stop with being inconsistent. Sometimes I worry the entire 90 minutes cause I don't know when our players will lose concentration and concede goals.— Sandile Khubisa (@sandile_khubisa) March 16, 2019
I am afraid that this will not be enough to go to semi-final. We have to many below average players in squad.— Uros Djokic (@urosdjokic) March 16, 2019
We're dead— True African Gent (@Arthur2Goodie) March 16, 2019
Its alright saying it but action speaks louder than words @HKane— James (@applescruff81) March 16, 2019
City like to bottle the champions league about this stage normally— Pikey87 (@Dier_Eric15) March 16, 2019
We know u will harry.....let’s show them who we are COYS— Charlotte (@Charpercy84) March 16, 2019
If we have ambitions to win it, you have to beat the likes of City. Need to leverage the crowds, Spurs historically have better success in Europe than them, down to fans to make them aware of that at home, and away. Worked so well for Liverpool. #COYS— FutbolDave (@davesluff) March 16, 2019
remember what people said when we drew dortmund— Goat (@cursedwizard01) March 16, 2019
The quarter-final first-leg could potentially be one of Tottenham's first games at their new stadium on 9 April, before the return leg at the Etihad Stadium on 17 April.