Leeds go into this top of the table clash with Kiko Casilla in goal, behind a back four of Luke Ayling, Pontus Jansson, Liam Cooper and Ezgjan Alioski.
Kalvin Phillips starts in holding midfield, with midfield help from Mateusz Klich and number 10 Tyler Roberts, who will be supporting the attack.
Jack Harrison and Pablo Hernandez will line up out wide, with Patrick Bamford given the nod to lead the Leeds attack once again.
Winger Jack Clarke returns to the squad for the first time in more than a month as he is named on the bench, having fallen ill at Middlesbrough in February.
He is joined by Bailey Peacock-Farrell, Barry Douglas, Gaetano Berardi, Jamie Shackleton, Robbie Gotts and Stuart Dallas.
Meanwhile, Sheffield United start with Dean Henderson between the sticks, as he looks to atone for the error which saw the Blades lose to Leeds back in December.
Chris Wilder goes with a back three again, with Jack O'Connell, John Egan and Martin Crainie starting, pushing Chris Basham into midfield it seems.
George Baldock and Enda Stevens line up as wing backs, with John Fleck and Oliver Norwood joining Basham in the Blades midfield.
Billy Sharp and David McGoldrick start up front, meaning Scott Hogan has to make do with a place on the bench.
Hogan is joined by fellow substitutes John Lundstram, Kieran Dowell, Mark Duffy, Paul Coutts, Richard Stearman and goalkeeper Simon Moore.
- Kiko Casilla
- Luke Ayling
- Liam Cooper
- Pontus Jansson
- Jack Harrison
- Pablo Hernández
- Mateusz Klich
- Kalvin Phillips
- Ezgjan Alioski
- Patrick Bamford
- Tyler Roberts
Substitutes: Bailey Peacock-Farrell, Gaetano Berardi, Barry Douglas, Robbie Gotts, Stuart Dallas, Jamie Shackleton, Jack Clarke.
- Dean Henderson
- George Baldock
- Chris Basham
- Martin Cranie
- John Egan
- Jack O'Connell
- Enda Stevens
- John Fleck
- Oliver Norwood
- David McGoldrick
- Billy Sharp
Substitutes: Simon Moore, Richard Stearman, Paul Coutts, Kieran Dowell, Mark Duffy, John Lundstram, Scott Hogan.