The names of any potential targets have yet to be disclosed, however - barring that of Mason Holgate, the Everton right-back who has since joined West Bromwich Albion on a temporary basis.
But if it is Premier League loans that Bruce is eyeing, then developments at one of the 58-year-old's former clubs may be of interest.
And a Championship spell could suit the Dutch right-back, whose previous loan to Crystal Palace did not go entirely as expected.
Given Bruce's strong Manchester United ties - which he used to acquire Axel Tuenzebe on loan for Aston Villa as recently as the start of this season - Wednesday could be at the front of the queue for any fringe players of which the Red Devils intend to dispose this winter.
And Fosu-Mensah looks set to be one of them.
Would the Fulham loanee be a good addition for Sheffield Wednesday?