Tottenham midfielder played no part in under-23 tie.
Skipp made his Premier League debut against Southampton in midweek as a 87th minute substitute in the 3-1 victory at Wembley.
Tottenham have made it clear that Skipp is being regarded as a first team player for the time being, leaving him out of today's under-23 tie.
Skipp did not feature at all in Tottenham's under-23 match with Everton, despite making five appearances for the side this season.
In recent weeks he has been with the first team, and Tottenham have made it evident they wish for this to continue.
The exciting 18-year-old is likely to feature on the bench against Leicester City as Spurs look to record back to back wins.
Tottenham have to balance their team selection with the midweek tie against Barcelona in mind.
There is an outside chance that Skipp is handed his first ever start if Spurs boss Mauricio Pochettino decides to rotate his squad.
Tottenham's midfield options are more limited by injuries to Victor Wanyama and Mousa Dembele.