Arsenal starting line-up: Leno; Bellerin, Sokratis, Holding, Mustafi, Kolasinac; Xhaka, Torreira; Mkhitaryan, Iwobi; Aubameyang
Arsenal substitutes: Cech, Lichtsteiner, Maitland-Niles, Guendouzi, Elneny, Ramsey, Lacazette
Tottenham Hotspur starting line-up: Lloris, Aurier, Vertonghen, Foyth, Davies, Dier, Alli, Sissoko, Eriksen, Son, Kane
Tottenham Hotspur substitutes: Gazzaniga, Alderweireld, Rose, Walker-Peters, Winks, Lucas, Llorente.
Arsenal head into the game having beaten Vorskla Poltava 3-0 in the Europa League on Thursday night, with Unai Emery rotating his side for the games.
Bernd Leno starts in goal, and he will be protected by a back five of Hector Bellerin, Sokratis Papastathopoulos, Rob Holding, Shkodran Mustafi and Sead Kolasinac.
Granit Xhaka partners Lucas Torreira in midfield, with Henrikh Mkhitaryan and Alex Iwobi supporting Pierre-Emerick Aubameyang in attack, as Alexandre Lacazette is only fit for the bench.
Fellow substitutes Petr Cech, Stephan Lichtsteiner, Ainsley Maitland-Niles, Matteo Guendouzi, Mohamed Elneny and Aaron Ramsey join him on the bench.
Meanwhile, Spurs come into the game after two big results, beating Chelsea 3-1 and Inter Milan 1-0 at Wembley, with another win in a big game needed today, this time on the road.
Hugo Lloris starts in goal, with a back four of Serge Aurier, Juan Foyth, Jan Vertonghen and Ben Davies in defence, as Toby Alderweireld is only named on the bench.
Eric Dier will play in holding midfield with support from Moussa Sissoko and Christian Eriksen, whilst Son Heung-min and Dele Alli will join Harry Kane in attack.
Paulo Gazzaniga, Danny Rose, Kyle Walker-Peters, Harry Winks, Lucas Moura and Fernando Llorente join Alderweireld on the bench this afternoon.