Bannan picked up his fifth yellow card of the season against Leeds United on Friday, and leaves (despite his 5ft 7ins frame) a sizeable hole to fill in central midfield.
Here's three ways Wednesday could do it...
Recall their Tottenham loanee
Josh Onomah has appeared in just two of a possible five matches since his loan from Tottenham began - his only start coming as a holding midfielder alongside Bannan against Nottingham Forest. Onomah, though, would prefer to play a more attacking role and could get his chance with Scotland star out. With Joey Pelupessy and potentially Michael Hector as cover, Onomah would be free to run between the lines (something Wednesday have perhaps lacked in Kieran Lee's absence) - albeit at the expense of a controlling presence such as Bannan's.
The winger was arguably the Owls' most threatening player against Leeds, scoring his side's only goal in spectacular style. But Reach has previous in Bannan's role, which he filled - and in which he thrived - for large parts of the 28-year-old's absence last season. And while Wednesday would miss the presence of their number 20 further upfield, they are not short of options to replace him, with Lucas Joao, Marco Matias (fitness depending), Fraser Preston and even Onomah capable of stepping in.
Change the system
While Sheffield Wednesday's switch to three at the back may have yielded four points from two very difficult fixtures, Luhukay could revert to a four in his quest to fill the void left by Bannan. Deploying Onomah and Reach either side of a screening player (most likely Pelupessy or Hector) would double the Owls' number of runners from central midfield, although it could leave them exposed against the Championship's best attack.
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