While Jan Vertonghen has really stepped up in recent months, Toby Alderweireld entered the season regarded as the team's top defender.
New signing Davinson Sanchez has done well, but Spurs were exposed at the weekend against Manchester City and really appeared to miss Alderweireld's know-how.
He was omitted from the squad as he has been since returning from his injury, as his contract stand-off continues.
Tottenham fans are understandably frustrated with the situation, and with a game against Brighton in midweek, they are keen for Alderweireld to get another chance.
Not only will it take Sanchez out of the firing line after a difficult game, but it would be a sign that Spurs still harbour some hope of repairing the damaged situation for Alderweireld.
During their recent unbeaten run, fans have been confident they can hope without the Belgian.
The loss at the weekend changes that, especially with a season defining FA Cup semi-final on the horizon, and manager Mauricio Pochettino has a big decision to make.
Youngster Juan Foyth is an alternative if Spurs want to shake up their options, but Alderweireld is the tried and trusted alternative who fans would prefer to see.
Here is a look at the discussion on Twitter...
Spurs are so poor defence awful. Can’t see us winning anything in the near future. Surely Toby needs to play on Tuesday v Brighton and maybe against United too— Noel (@TommythePort) April 14, 2018
If Toby is still a) alive and b) has any hamstrings whatsoever, he surely plays against Brighton on Tuesday— Charles COYS (@charlesrich82) April 14, 2018
Sanchez has looked shattered tonight, he will have to play on Tuesday & then again next Saturday for our biggest game of the season, he is only 21. He needs a rest. Get Toby on the pitch.— Nad (@nad_THFC) April 14, 2018
Spurs need to start playing alderweireld #EndOf give him the wages he wants— Ally Macleod (@AllyButtons) April 15, 2018
Poch been saying Toby has to earn his place back after our defence has been so good since his time out!After yesterday Brighton squad will be interesting!! #COYS— Lenco10 (@Foady10) April 15, 2018
Poch really needs to bless the beef with Alderweireld. Glass of wine, bit of take that - back for good. We do sly need him back— George Montella (@georgemontella) April 14, 2018