The youngster will join up with the Doonhammers until the end of the season.
Queens currently sit fifth in Championship table with eight wins from 21, three points behind fourth-placed Livingston.
Hearts were reportedly keen on a loan move for Cameron earlier this week according to the Scotsman, with Craig Levein keen on bolstering his defensive options; however, the move never materialised.
Cameron, an English-born Scottish under-21 international, is yet to make his senior debut for Newcastle. Yet he has enjoyed loan spells away with Workington, York City and Newport County.
Speaking to the club website, Queens manager Gary Naysmith said: “I am delighted that Kyle has agreed to join us. He is a left sided defender who turned 21 on Monday, he is comfortable playing as a central defender in a back three or a back four and can also fill in as an emergency left back if required.
“At over 6ft2in he gives us a height and although only 21 has played for Scotland U17s, 19s and U21s.
“[He] will provide good competition for Darren Brownline and Callum Fordyce in the central defensive area of our team.”
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