Jagielka is Everton's most experienced defender when it comes to Merseyside derbies.
Sam Allardyce has plenty to think about ahead of the Merseyside derby. After back-to-back wins, the new Everton boss has some selection headaches right across the pitch.
One of those will be in defence. For the victories against West Ham United and Huddersfield Town, Mason Holgate and Ashley Williams have played at centre-half and have performed well.
That leaves Michael Keane and Phil Jagielka as their other central defensive options. 21-year-old Holgate has played six Premier League games this season and has only ever played in one Merseyside derby. That came in the 3-1 defeat at Anfield and it proved to be a tough day for the youngster.
Allardyce may want a more experienced back line against Liverpool's deadly attack. Jagielka has played in 17 Merseyside Derbies and will not be fazed by the occasion. The 35-year-old has been one of England's best performing centre-halves over the last decade although his performances have been questionable this term. His last appearance came in the 4-1 demolition by Southampton so his confidence has been knocked slightly.
Williams is likely to start as he has looked back to his best in the last couple of games and on paper and you could argue he is Everton's best defender.
'Big Sam' could opt to play five at the back given Liverpool's potent attack. Everton will have to deal with the likes of Mohamed Salah, Philippe Coutinho and Roberto Firmino so should Allardyce play three central defender's, then Jagielka has to be one of them.
Out of Everton's four centre-halves, Keane is the one who has looked the most out of sorts recently. He too has been left out of the side for the last two victories. Starting Jagielka over Holgate would perhaps be the safer option although it will not please all Everton fans but if Allardyce plays a back-three then Jagielka is surely a must.