Gary Megson takes caretaker charge of West Brom for the first time following Tony Pulis' sacking earlier this week at the weekend, and there are arguably few more daunting fixtures the 58-year-old could be handed first up.
The Baggies travel to Wembley to face a Tottenham side that secured top spot in their Champions League group in midweek and can now concentrate most of their attention on the league for the next few weeks at least.
With a change of manager, it would be no surprise to see a number of changes made to the team by Megson. But, of course, with the caretaker boss working under Pulis before his departure, there may not be as many changes as the supporters would like.
Firstly, there may perhaps be a slight change in system, with West Brom reverting to more of a 4-5-1 shape to try and keep things tight against Mauricio Pochettino's side.
That may see Allan Nyom come back in at right-back, thus giving Matt Phillips the freedom to not worry about playing as a wing-back as he did against Chelsea.
Meanwhile, Claudio Yacob brought some bite to the team against the Blues after coming on at half-time for Grzegorz Krychowiak, so he may replace Jake Livermore at Wembley - though it could quite easily by the Poland international who drops out if Yacob comes in.
And of course, it must not be forgotten that Yacob has history with Spurs' Dele Alli, so Megson may be hoping that he gets under the midfielder's skin once again.
The other change comes on the left-wing with Oliver Burke making his first Premier League start since his summer move to The Hawthorns. He has the potential to make something special happen, and the Baggies should be throwing a couple of those unpredictable players in in the hope that they can produce the magic to surprise Tottenham.
With that in mind, here is the lineup we are expecting in full...