Rafa Benitez will take his Newcastle side to Hillsborough on the back of consecutive wins in the Championship, and just one defeat in their last 15 league outings, which has seen them maintain their position at the top of the table.
Wednesday, meanwhile, have won just one of their last five games, and sit in sixth spot, with a two point lead over seventh placed Fulham.
And Prutton made his prediction for Sky Sports, sharing how he believes there will be plenty of goals in South Yorkshire tomorrow:
"You can see Newcastle doing what they did to the likes of Huddersfield at Sheffield Wednesday, allowing them to dominate the ball and hitting them on the counter. Automatic promotion is paramount for Newcastle, but because of the cushion they have in the top two, and with Wednesday needing a result to stay in the pack, I think it will be a draw."
Sheffield Wednesday's manager Carlos Carvalhal
Prediction: Sheffield Wednesday 2-2 Newcastle United
The Tyneside outfit currently hold a 10 point advantage over third placed Huddersfield Town, so it could be argued that Carlos Carvalhal's men are in more desperate need of the points than Benitez' side.
The Magpies will be looking to take another step towards wining the league, however, and a victory against the Owls would see them set a new club record, with what would be their 14th away victory this season, eclipsing the 13 away wins enjoyed by Kevin Keegan's side during the 1992/93 campaign.
Newcastle United manager Rafa Benitez
Have something to tell us about this article?