Jose Mourinho's side head to the Hawthorns looking to stretch their unbeaten run - here is how you can see all the action.
The Baggies were expected to be scrapping it out in mid-table rather than flirting with Europe, while many anticipated a United title challenge given their expensive summer recruitment both in the dugout and on the pitch.
Mourinho's men have improved of late, and visit the West Midlands protecting a run that has seen them go seven matches without defeat in the Premier League. Albion, meanwhile, have won four of their last six matches as they continue to surpass expectations.
West Brom's Salomon Rondon scores their first goal
The Key Battle - Salomon Rondon vs Phil Jones
Rondon's 13-minute hat-trick in the midweek win over Swansea was the latest instalment of his impressive season, and took his 2016/17 tally to seven.
Looking to stop the in-form striker will be Phil Jones, who has been solid since his return to the United back four after a lengthy injury lay-off.
Manchester United's Phil Jones
The Baggies claimed a 1-0 win in March's meeting at the Hawthorns, with Rondon's strike punishing a 10-man United side who had earlier seen Juan Mata sent off.
That was the latest of 43 Albion victories in this fixture, with United having emerged victorious on 54 occasions.
Manchester United's Memphis Depay in action with West Brom's Craig Gardner
Recent league form – most recent last:
West Brom - WWDWLW
Manchester United - WDDDWW
Who’s the ref?
Anthony Taylor will be the man in the middle for this one.
The 38-year-old showed the most recent of his three red cards this season in midweek as Marko Arnautovic was given his marching orders in Stoke's goalless draw with Southampton.
Manchester United's Zlatan Ibrahimovic celebrates after the match with Paul Pogba
What time is kick off?
West Brom v Manchester United starts at 5.30pm.
Where can I watch it?
BT Sport 1 is the place to catch the action from the Hawthorns, with coverage beginning at 5pm.
West Brom - 17/4
Draw - 11/4
Manchester United - 4/6
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