West Ham United manager Slaven Bilic
The Hammers are one point and one place above the relegation zone after a woeful record of seven defeats from their opening 12 games this season.
The latest came at White Hart Lane last time out as they threw away a 2-1 lead with just minutes left to lose 3-2 to bitter rivals Tottenham Hotspur.
West Ham have the second worst defensive record in the Premier League with only Hull conceding more.
Slaven Bilic's side are struggling at the other end too highlighted by the fact not one of the club's strikers has scored a single goal this season 18 competitive games in.
West Ham United's Simone Zaza looks dejected
The Hammers also hold the unwelcome record of squandering the most points in the league, giving away eight from winning positions so far - a haul which would now see them sitting joint sixth in the table instead of 17th.
Mauro Zarate's profligacy and the woodwork stopped West Ham winning at Old Trafford last season
In the league, Bilic's Hammers were denied another big scalp on the road when West Ham hit the post and bar no fewer than four times while former striker Mauro Zarate could have had a hat-trick in a 0-0 draw.
Then in the FA Cup quarter-finals West Ham were again superior and took the lead thanks to Dimitri Payet's amazing free-kick only to be held to a replay when Anthony Martial's goal was allowed to stand despite calls for offside and a blatant foul on goalkeeper Darren Randolph.
Payet was also fouled when through on goal with the score at 1-0 but the referee waved away appeals.
Anthony Martial scores Manchester United's controversial equaliser back in March
West Ham went on to lose the replay at Upton Park leaving a bitter taste in the mouths of the Hammers faithful.
Now on the eve of Sunday's visit to Old Trafford in the Premier League - and without key defender Winston Reid available as he serves a one-match suspension - Bilic faces the headache of the hosts's star striker boosted by a surprising new contract.
Pumped up: Manchester United's Zlatan Ibrahimovic
The Swede's new deal has raised eyebrows among pundits and supporters alike and he will be out to prove everyone wrong against a weakened line-up of what is already the second worst defence in the top flight.
With Wayne Rooney also looking sharp with a goal against Feyenord in the Europa League in midweek West Ham will have to be on their game to stop the hosts.