City will take on Liverpool at the Etihad Stadium in the Premier League on Saturday evening, and Keown expects the home team to pick up all three points.
“To manage at Liverpool you need a big personality, and Klopp certainly has that,” the former England international wrote in The Daily Mail. “But this is his biggest test so far.
"Yes, they went to Stamford Bridge and won, but so have other teams this season. They are capable of pulling off a surprise at City but I still think the home side will be too strong.”
Liverpool will be looking to return to winning ways on Saturday evening when they take on City away from home in the Premier League.
The Reds will head into the encounter at the Etihad Stadium on the back of a 2-1 defeat to Crystal Palace at Anfield.
The loss to Palace just before the two-week international break brought to an end Liverpool’s three-match winning run in all competitions.
The defeat was also Jurgen Klopp’s first since he replaced Brendan Rodgers as the Liverpool manger last month.
The Merseyside outfit are 10th in the Premier League table at the moment with 17 points from 12 matches.
Meanwhile, City currently find themselves at the top of the standings with 26 points from 12 games.