Argentine winger Angel Di Maria looks set for a spell on the sidelines.
Manchester United have had a series of injury problems this season. The likes of Radamel Falcao, Ander Herrera, Daley Blind, Chris Smalling, Phil Jones, Jonny Evans, Luke Shaw, Rafael, Ashley Young, Michael Carrick and more have been or are currently injured for the club.
In fact, before the game with Hull City this afternoon Manchester United have suffered 40 separate injuries to first team players since the start of the season, a whopping total.
That count has now gone up to 41 - with their club record signing the most recent addition.
Argentine Angel Di Maria signed for the club from Real Madrid in the summer for a fee in the region of £59.7 million.
Now the Manchester United superstar looks set to be out of action for a while, as he limped out of the game with a hamstring problem - being replaced by Ander Herrera.
He was on a trademark charge up the pitch when he pulled up lame and Louis van Gaal is going to have to deal with yet another injury problem.
United fans will hope the injury is not severe.