Netting a brace in the match with the Greek side, it was his first astonishing effort that will live long in the memory of the watching Spurs faithful.
The ball broke to Lamela on the edge of the area after good work by Emmanuel Adebayor, and the 22-year-old wrapped his left foot behind his standing right leg and smashed a wonderful flick into the top corner past Tomas Kosicky in the Asteras goal.
It happened so quick that at first glance it looked as if he had merely struck it with his right, but the sheer audacity and class of the goal would only dawn on viewers watching in slow motion.
It was a strike that offered a peek at the undeniable skill and flair the young Argentine is capable of, something that is too often glossed over as result of his injury problems and heavy price tag.
But the brutal truth is that there are precious few players in world football that would be capable of such a goal in a professional game.
It is sure to be a goal talked about for years at White Hart Lane, regardless of what kind of career Lamela goes on to have in North London.
But if anything is going to fire the former Roma man onto bigger and better things, especially in the Premier League, it is a performance like he put in against Asteras, where he benefitted from trusting in his ability.