Tottenham Hotspur starting XI: Lloris; Emerson, Dier, Romero, Davies; Skipp, Hojbjerg, Lo Celso; Lucas, Son, Kane.
Tottenham Hotspur substitutes: Gollini, Sanchez, Tanganga, Rodon, Doherty, Reguilon, Dele, Ndombele, Bergwijn.
Manchester United starting XI: De Gea; Wan-Bissaka, Lindelof, Maguire, Varane, Shaw; Fred, McTominay; Fernandes, Ronaldo, Cavani.
Manchester United substitutes: Henderson, Bailly, Dalot, Lingard, Matic, Van de Beek, Greenwood, Rashford, Sancho.
Tottenham Hotspur go with Hugo Lloris in goal, and there is a surprise change at left back with Ben Davies coming in for Sergio Reguilon.
Emerson Royal, Eric Dier and Cristian Romero join Davies in defence, with Oliver Skipp and PIerre-Emile Hojbjerg in midfield.
Giovani Lo Celso is the number 10, with Lucas Moura and Son Heung-min flanking Harry Kane up top.
Reguilon drops to the bench alongside Tanguy Ndombele, Pierluigi Gollini, Davinson Sanchez, Japhet Tanganga, Joe Rodon, Matt Doherty, Dele Alli and Steven Bergwijn.
Manchester United appear to be going with a five-man defence with Raphael Varane, Harry Maguire and Victor Lindelof all starting in front of goalkeeper David De Gea.
Aaron Wan-Bissaka and Luke Shaw are the wing backs, with Fred and Scott McTominary in the middle of the park.
Bruno Fernandes will operate behind a front two of Cristiano Ronaldo and Edinson Cavani.
That means Mason Greenwood, Marcus Rashford and Jadon Sancho are all on the bench, joining Dean Henderson, Eric Bailly, Diogo Dalot, Jesse Lingard, Nemanja Matic and Donny van de Beek.
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