Southampton starting XI: McCarthy, Walker-Peters; Stephens, Vestergaard, Salisu; Ward-Prowse, Armstrong; Djenepo, Tella; Adams, Walcott.
Southampton substitutes: Forster, Bednarek, Diallo, Ferry, Minamino, Redmond, Obafemi, Nlundulu, Ings.
Leeds United starting XI: Casilla; Ayling, Llorente, Cooper, Alioski; Phillips, Dallas; Raphinha, Rodrigo, Harrison; Bamford.
Leeds United substitutes: Meslier, Struijk, Davis, Berardi, Shackleton, Jenkins, Roberts, Hernandez, Poveda.
Southampton go with Alex McCarthy in goal, behind a back four of Kyle Walker-Peters, Jack Stephens, Jannik Vestergaard and Mohammed Salisu.
James Ward-Prowse will work with Stuart Armstrong in central midfield, whilst Moussa Djenepo and Nathan Tella will flank Che Adams and Theo Walcott in attack.
Danny Ings is only on the bench, joining Fraser Forster, Jan Bednarek, Ibrahima Diallo, Will Ferry, Takumi Minamino, Nathan Redmond, Michael Obafemi and Dan Nlundulu.
Leeds make a surprise change in goal as Kiko Casilla starts in place of Illan Meslier, whilst Liam Cooper comes in for Pascal Struijk at centre back.
Luke Ayling, Diego Llorente and Ezgjan Alioski make up the rest of the back four, with Kalvin Phillips and Stuart Dallas in midfield.
Rodrigo starts as the number 10 tonight, joining Raphinha and Jack Harrison in supporting Patrick Bamford up top.
Tyler Roberts joins Meslier, Struijk and Mateusz Klich on the bench, along with Leif Davis, Gaetano Berardi, Jamie Shackleton, Jack Jenkins, Pablo Hernandez and Ian Carlo Poveda.
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