Southampton starting XI: McCarthy; Valery, Stephens, Bednarek, Vokins; Diallo, Ward-Prowse; Armstrong, Walcott; Ings, Adams.
Southampton substitutes: Forster, Ramsay, Jankewitz, Ferry, Watts, Chauke, Redmond, N’Lundulu, Long.
Arsenal starting XI: Leno; Bellerin, Luiz, Holding, Cedric; Xhaka, Partey; Pepe, Smith Rowe, Saka; Lacazette.
Arsenal substitutes: Ryan, Gabriel, Chambers, Maitland-Niles, Elneny, Willock, Willian, Martinelli, Nketiah.
Southampton go with Alex McCarthy in goal, behind a youthful back four of Yan Valery, Jack Stephens, Jan Bednarek and Jake Vokins.
Ibrahima Diallo partners James Ward-Prowse in midfield, with Stuart Armstrong and Theo Walcott supporting Danny Ings and Che Adams in attack.
Nathan Redmond is on the bench, alongside Fraser Forster, Kayne Ramsay, Alex Jankewitz, Will Ferry, Caleb Watts, Kgagelo Chauke, Dan N’Lundulu and Shane Long.
Arsenal have Bernd Leno between the sticks, though Kieran Tierney misses out due to a knock sustained to his right leg, meaning Cedric Soares faces his former club at left back.
Hector Bellerin, David Luiz and Rob Holding make up the rest of the back four, whilst Granit Xhaka partners Thomas Partey in midfield.
Bukayo Saka switches to the left flank with Pierre-Emerick Aubameyang out of action, meaning Nicolas Pepe gets a chance on the right.
Emile Smith Rowe features as the number 10, working behind Alexandre Lacazette in the Arsenal attack.
Mat Ryan is on the bench following his move from Brighton and Hove Albion, with Gabriel, Calum Chambers, Ainsley Maitland-Niles, Mohamed Elneny, Calum Willock, Willian, Gabriel Martinelli and Eddie Nketiah.
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