Manchester United starting XI: De Gea; Dalot, Lindelof, Maguire, Telles; Fred, McTominay; Sancho, Fernandes, Rashford; Ronaldo.
Manchester United substitutes: Henderson, Bailly, Jones, Lingard, Mata, Van de Beek, Diallo, Greenwood, Martial.
Arsenal starting XI: Ramsdale; Tomiyasu, White, Gabriel, Tavares; Elneny, Partey; Martinelli, Odegaard, Smith Rowe; Aubameyang.
Arsenal substitutes: Okonkwo, Tierney, Holding, Maitland-Niles, Lokonga, Pepe, Saka, Lacazette, Nketiah.
Manchester United go back to a 4-2-3-1 tonight as David De Gea starts in goal.
Harry Maguire returns in defence, joining Diogo Dalot, Victor Lindelof and Alex Telles at the back.
Fred and Scott McTominay are in midfield, with Jadon Sancho, Bruno Fernandes and Marcus Rashford supporting Cristiano Ronaldo up top.
Youngster Amad Diallo is on the bench, joining Dean Henderson, Eric Bailly, Phil Jones, Jesse Lingard, Juan Mata, Donny van de Beek, Mason Greenwood and Anthony Martial.
Arsenal go with Aaron Ramsdale in goal whilst Nuno Tavares again gets the nod over Kieran Tierney at left back.
Takehiro Tomiyasu, Ben White and Gabriel Magalhaes join Tavares in defence, with Mohamed Elneny joining Thomas Partey in midfield.
Martin Odegaard starts again as the number 10, with Gabriel Martinelli and Emile Smith Rowe out wide.
Pierre-Emerick Aubameyang is the lone striker for Arsenal tonight.
Bukayo Saka is only on the bench after suffering an injury against Newcastle United at the weekend.
Arthur Okonkwo, Tierney, Rob Holding, Ainsley Maitland-Niles, Albert Sambi Lokonga, Nicolas Pepe, Alexandre Lacazette and Eddie Nketiah make up the rest of the Arsenal bench tonight.
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