Arsenal starting XI: Leno; Maitland-Niles, Holding, Gabriel, Tierney; Elneny, Ceballos, Saka; Pepe, Aubameyang, Nketiah.
Arsenal substitutes: Runarsson, Cedric, Luiz, Mustafi, Willock, Willian, Lacazette.
Southampton starting XI: McCarthy; Walker-Peters, Vestergaard, Bednarek, Bertrand; Romeu, Ward-Prowse; Armstrong, Walcott; Ings, Adams.
Southampton substitutes: Forster, Stephens, Salisu, Diallo, Djenepo, Redmond, N’Lundulu.
Arsenal go with Bernd Leno in goal, behind what appears to be a back four of Ainsley Maitland-Niles, Rob Holding, Gabriel Magalhaes and Kieran Tierney.
Dani Ceballos starts in midfield with Granit Xhaka suspended, with Mohamed Elneny and Bukayo Saka also in the engine room.
Nicolas Pepe starts on the right flank, with Pierre-Emerick Aubameyang on the left and Eddie Nketiah up top.
That means Willian is on the bench, alongside Runar Runarsson, Cedric Soares, David Luiz, Shkodran Mustafi, Joe Willock and Alexandre Lacazette.
Southampton have Alex McCarthy between the sticks, and he’ll play behind a back four of Kyle Walker-Peters, Jannik Vestergaard, Jan Bednarek and Ryan Bertrand.
James Ward-Prowse joins Oriol Romeu in midfield, with Theo Walcott and Stuart Armstrong supporting Che Adams and Danny Ings up top.
Nathan Redmond is on the bench, with Fraser Forster, Jack Stephens, Mohammed Salisu, Ibrahimo Diallo, Moussa Djenepo and Dan N’Lundulu.
Receive exclusive football transfer news and updates twice a week to your mailbox
