Arsenal starting XI: Leno; Bellerin, Holding, Luiz, Cedric; Partey, Xhaka; Pepe, Smith Rowe, Martinelli; Lacazette.
Arsenal substitutes: Runarsson, Gabriel, Chambers, Maitland-Niles, Elneny, Willock, Odegaard, Willian, Nketiah.
Manchester United starting XI: De Gea; Wan-Bissaka, Lindelof, Maguire, Shaw; McTominay, Fred; Pogba, Fernandes, Rashford; Cavani.
Manchester United substitutes: Henderson, Telles, Bailly, Tuanzebe, James, Matic, Van de Beek, Greenwood, Martial.
Arsenal go with Bernd Leno in goal, behind a back four of Hector Bellerin, Rob Holding, David Luiz and Cedric Soares, with Kieran Tierney still out.
Thomas Partey partners Granit Xhaka in midfield, whilst Gabriel Martinelli is in on the left flank in place of the injured Bukayo Saka, who misses out with a hip problem.
Emile Smith Rowe is the number 10 with Nicolas Pepe down the right, whilst Alexandre Lacazette leads the line with Pierre-Emerick Aubameyang still missing.
New signing Martin Odegaard is on the bench, but there is no sign of Mat Ryan as Runar Runarsson joins Gabriel Magalhaes, Calum Chambers, Ainsley Maitland-Niles, Mohamed Elneny, Joe Willock, Willian and Eddie Nketiah as a substitute.
David De Gea starts in goal for United, with Aaron Wan-Bissaka, Victor Lindelof, Harry Maguire and Luke Shaw ahead of him.
Scott McTominay joins Fred in midfield, whilst Marcus Rashford, Bruno Fernandes and Paul Pogba will support Edinson Cavani up top.
That means Anthony Martial is only a substitute, alongside Dean Henderson, Alex Telles, Eric Bailly, Axel Tuanzebe, Daniel James, Nemanja Matic, Donny van de Beek and Mason Greenwood.
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