The Magpies have been linked with a move for the Mexican recently.
Defender says he felt Villarreal were the best option for his career.
With one defensive target ruled out, Chancel Mbemba might yet have a future at Newcastle United.
Newcastle had been strongly tipped to sign Ruben Semedo.
Leeds United looked to have warded off interest from Southampton for Pontus Jansson but the Ruben Semedo saga may change things.
Newcastle United had been tracking Sporting Lisbon defender Ruben Semedo for much of the summer so far.
Newcastle United are expecting to complete the signing of Portuguese defender Ruben Semedo.
Southampton and Newcastle United are both interested in signing Sporting Lisbon defender Ruben Semedo this summer.
The Spanish side are also keeping an eye on the Sporting Lisbon and Portugal defender, and have decided to join the race.
Newcastle United's move for Ruben Semedo still has hurdles to overcome.