Leeds United's Pontus Jansson faces Cristiano Ronaldo during the international break.
Portugal's best showing in the World Cup was 1966 when they finished third, they also finished fourth in 2006. The majority of their players are made up from La Liga and the Portuguese Primeira Liga.
Championship boss Garry Monk signed Eder for Swansea City last summer, a deal which led to his downfall.
Everton were once reportedly keen on striker Eder, who scored the winning goal for Portugal against France in the Euro 2016 final.
The Southampton defender featured for Portugal against France in the Euro 2016 final on Sunday evening.
Portugal were surprise winners in a different if underwhelming tournament.
The Sheffield Wednesday manager has also criticised Dimitri Payet’s tackle on Cristiano Ronaldo during the Euro 2016 final between Portugal and France.
France were beaten by Portugal in the final of Euro 2016 on Sunday.
The West Ham United star made a tackle on the Real Madrid ace during the Euro 2016 final between Portugal and France.
Real Madrid were linked with wanting to sign Dimitri Payet from West Ham... but will they now?
Newcastle's Moussa Sissoko impressed in the Euro 2016 final for France.
Manchester United target Andre Gomes featured for Portugal against Iceland.
William Carvalho impressed as Portugal drew 0-0 with Austria on Saturday.
Wales' Euro 2016 semi-final against Portugal is billed as Gareth Bale vs Cristiano Ronaldo but a West Ham United star will be the most important player.
Cristiano Ronaldo has distanced himself from criticism that he thrives on individual success.
The Portuguese forward is apparently seen as the ideal replacement for Sofiane Feghouli who has joined West Ham.
Former Manchester United star Cristiano Ronaldo and loanee Nani are back at Old Trafford with Portugal.