The Sheffield Wednesday striker has failed to find the net since March.
Neil Mellor has praised Leeds United, and singled out Charlie Taylor for his excellent display.
Karius came under fire after Liverpool lost 4-3 to Bournemouth on Sunday.
The striker has struggled to make a major impact since joining Glasgow Rangers in the summer.
Jurgen Klopp made 11 changes to his line-up for the cup clash with Spurs on Tuesday night.
The former Dortmund coach has certainly had an impact at Anfield, but has the absence of a world-class superstar proved a help rather than a hindrance?
Newcastle United defeated Rotherham United 1-0 in Yorkshire.
The forward joined Liverpool from Southampton this summer.
The ex-Liverpool striker is excited about the Reds' most recent signing from Southampton.
Sheffield Wednesday lost the play off final to Hull City on Saturday.