Arsene Wenger is likely to rotate his squad heavily for the EFL clash with Reading - a fixture that ended 7-5 on a crazy night for both sides a few years ago.
Arsenal have a number of tireless players in their squad.
Arsenal defeated Burnley 1-0 at Turf Moor on Sunday.
Francis Coquelin suffered a knee injury in Arsenal's 3-0 win against Chelsea, and his absence could be more detrimental to the team than many fans think.
Arsenal take on Basel off the back of a stunning 3-0 victory over Chelsea. However, the Swiss club have an excellent record against English opponents.
Arsenal came back from conceding after 42 seconds to draw 1-1 with PSG in the Champions League.
Jack Wilshere's loan departure shows that Arsene Wenger is confident in his central midfield options.
With the transfer window now closed, Tottenham Hotspur, Bournemouth and Chelsea all made headline moves that are viewed as smart business.
The forward was a star for Chile as they won their second Copa America.
The Egyptian midfielder has been a big hit since arriving at Arsenal in January.