The Black Cats were beaten 2-1 by Middlesbrough on Sunday.
A defeat for Moyes while Karanka sees his side pick up their first victory after their return to the Premier League, but how did the players fare?
Joel Matip and Marko Grujic could be in line for the first competitive starts, while youngsters Ben Woodburn and Trent Alexander-Arnold could come into contention.
Hull City continued their great start to the Premier League season with a 2-0 victory over Swansea City on Saturday.
Name alone will not encourage the Celtic boss to land a marquee player
The Belgian striker was on the move yet again this week.
Just two games into his Black Cats career, David Moyes says Sunderland are in a relegation battle. Over to you, Twitter.
Future of Massimo Cellino's Leeds United ownership suddenly more uncertain.
Stars from Liverpool, Tottenham Hotspur and West Ham United feature among others.
City kept their seven-and-a-half year unbeaten steak going, but were lucky to to draw as Town had the better second half
The president of the Croatian football federation, Davor Suker, has congratulated the French authorities for the way they have handled trouble at the European Championship and urged his country’s government to act against hooligans, insisting that 99.9% of their supporters are well behaved.
“It’s not as if we have been knocked out,” Andrés Iniesta said, but it was exactly as if they had been knocked out.