Spurs thumped the Black Cats but only emerged with a 1-0 win.
The former Chelsea midfielder, who has scored 12 goals in his last 15 MLS appearances, has been ruled out for three to four weeks with a calf strain.
The Magpies were beaten 2-0 at St James' Park on Saturday.
The Hammers, along with Chelsea and Manchester pair United and City, were present during the 21-year-old's most recent outing.
Tottenham loanee admitted the last few weeks have been difficult for him.
The Belgium international spent two years on loan at Atletico Madrid before becoming Chelsea's number one goalkeeper.
The Blues are currently second in the table after the first five games of the season.
Daryl Murphy is yet to make his Newcastle United debut after joining from Ipswich Town in the summer.
Pickford is currently Sunderland's regular goalkeeper following an injury sustained by Vito Mannone.
Vincent Janssen is yet to score for Tottenham Hotspur since signing in the summer.
With three major championships in the bag, a 45th birthday to come next month and a subsequent date at Hazeltine as a Ryder Cup assistant captain, Padraig Harrington would be forgiven a pipe and slippers approach to life.
Antoine Walker opened up about the three biggest money lessons he learned.
As he became the first Canadian man to reach a grand slam final, Milos Raonic appeared not to know whether to laugh or cry. John McEnroe, acting as a coaching consultant to the big-serving Raonic, who secured victory over Roger Federer in five see-saw sets, had called on his charge to be more expressive on court.