City boss Guardiola admits both players could be handed their first competitive starts of the season.
DeAndre Yedlin spent last year on loan at Sunderland and could sign for rivals Newcastle.
Will Walter Zenga choose to change his team much for tonight's game against Cambridge?
Manchester United defeated Southampton 2-0 at Old Trafford.
The Tottenham attacking midfielder again demonstrated his exciting talent during the Under-23s' 4-1 win over Reading.
The midfielder is confident that Liverpool can get back to winning ways following their disappointing defeat at Turf Moor.
Reports suggest the Black Cats have turned down the opportunity to sign Sakho on loan.
Pep Guardiola's side are 5-0 up on aggregate against Steaua Bucharest as they welcome the Romanians to the Etihad on Wednesday.
The Championship side managed to bring the 27-year-old in on a permanent deal.
Everton defender Brendan Galloway has joined West Bromwich Albion on loan.