Ronald and Erwin Koeman took over at the club last summer.
Manager Tim Sherwood has provided a fitness update on his squad ahead of the weekend's Premier League clash with West Ham United at Villa Park.
The Crystal Palace boss signed the two players nine years ago.
David De Gea has to be tied up on a long-term contract to stop any possibility of a move to Real Madrid, says the former United favourite.
The Dutch international is not injured but is not strong enough for the game.
Former Germany international Dietmar Hamann has voiced a concern for Tim Sherwood ahead of the FA Cup final.
Cheikhou Kouyate joined West Ham United from Anderlecht in the summer of 2014.
Southampton have a number of players who are currently ruled out through injury.
Crystal Palace midfielder James McArthur is expecting his side to test Manchester United at the weekend.
Manuel Neuer put in a superb performance in goal for Bayern Munich, despite the German champions suffering a heavy defeat to Barcelona.