Rangers boss Mark Warburton threw Niko Kranjcar on in the second half at Ibrox.
The former Spurs midfielder enjoyed Kane playing in a deeper role.
Leeds United won against Sheffield Wednesday in the Championship on Saturday.
The defender has impressed this season for Ronald Koeman's men.
The 30-year-old striker failed to find the back of the net in Saturday's goalless draw at the iPro Stadium, but he still managed to show how crucial he will be to Roberto Di Matteo's side this season.
Crystal Palace have experienced a mixed weekend.
The Tractor Boys have not beaten their fiercest rivals since April 2009, have halted a four game losing streak in the league.
West Ham United defeated Bournemouth 1-0 at the Olympic Stadium.
The Atletico Madrid full back went on loan to Liverpool during the 2014-15 campaign
The Frenchman struggled in the second half of last season.