Pundit believes Tottenham will be too strong for Everton.
Merson is tipping a 2-0 victory for Spurs at Wembley despite Everton's recent resurgence.
Spurs beat Everton 3-0 at Goodison Park back in September, but the Toffees have improved since Sam Allardyce took over, especially defensively.
Despite this, Merson believes Tottenham will simply be too strong for Everton, who have lost back to back games against Manchester United and Liverpool, giving their recent optimism a little reality check.
The Tottenham game will be another tough test.
Merson said: "Spurs struggled at home to West Ham and it took them a while to break down AFC Wimbledon in the FA Cup.
"But I think they will have too much for an Everton side who are going to sit back and play tight. It has worked for them in the past, but they don't have enough pace on the counter to hurt Tottenham."
Tottenham are in fifth position in the Premier League, two points ahead of Arsenal and three behind fourth placed Liverpool.
Everton are up to ninth after a worrying start to the season which saw them switch managers, but they remain 14 points behind Tottenham.