West Ham are currently deeply embroiled in a relegation battle, and sit precariously in 19th position in the table, whilst tomorrow's opponents Chelsea are in the midst of an impressive run, and occupy third spot in the table.
Antonio Conte's men are heavy favourites to win the match at the London Stadium tomorrow, although Hammers fans will be looking to generate the type of atmosphere that will make it tough for the away team to play their football.
And Merson shared his belief that the game against Chelsea does not really matter to West Ham, as they have more important games around the corner, when writing his regular column for Sky Sports:
"These aren't the games that matter for West Ham. I know it is a London derby and they don't like each other. I don't expect them to get anything from this, but if you lose to Arsenal and Chelsea it isn't too bad. It is the games against Stoke, Newcastle and Bournemouth that matter most. Chelsea are a superior football team by far. West Ham's battles are still to come."
Whilst Merson's words are understandable to an extent, the Hammers are not in a position where they can afford to pick and choose what games they turn up for.
In fact, there is a notion that David Moyes' side actually play better against the bigger clubs, and they should be looking at the Chelsea match as nothing other than a great opportunity to pick up three points and kick-start their season.