Liverpool face Everton in the Merseyside derby on Sunday and are heavy favourites to get a win.
They have scored 12 goals in their last two games against Brighton and Spartak Moscow, while conceding just one.
New Everton boss Sam Allardyce has a big task ahead of him, and Merson believes Everton's only option is to go ultra defensive.
Merson said: "Everton are just going to come and park the bus and get 10 men behind the ball. Then, they will hope they'll get something from a set piece. It will be tight, but Liverpool are just too good at home.
"Liverpool are scoring goals for fun at the moment, and I know their Achilles heel is their defence, but I just don't see how Everton get at them. Sam Allardyce will do everything he can to make it a tight match, but that won't be enough."
Merson is predicting a 2-0 win for the Reds, and while this would not be a great result for Everton, it would at least spare them a big humiliation.
Liverpool are capable of ripping teams apart, and if they take an early lead against the Toffees it could be a long day for Allardyce's side.