The QPR defender has been out since September with a hamstring problem.
Onuoha has been sidelined since September with a hamstring problem that he suffered during the draw with Millwall but he is now in contention to feature against Leeds, as reported by Get West London.
The experienced defender is usually deployed as a centre-back but is also capable of operating at right-back if required and his return will represent a major boost for QPR, whose defensive options have been depleted in recent weeks due to a host of injuries.
Onuoha, QPR's captain, also possesses valuable leadership qualities and is exactly the type of figure that his side require at present.
QPR are in woeful form at present having lost four of their last five Championship fixtures and are in desperate need of points as they prepare to face a Leeds side that are determined to secure a place in the play-offs.
Holloway will hope that QPR's improving injury situation will lead to his side becoming more resilient at the back - they have conceded 29 goals in the Championship so far this season.