Reds boss Jüren Klopp will be desperate to bolster his defensive ranks during the January transfer window, and whilst ace Virgil van Dijk remains the German's number one target, the Saints' refusal to sell could mean that he has to explore different options.
With this in mind, a useful alternative for them could be Roma centre-back Kostas Manolas, and a cheaper one at that.
The 26-year-old has recently had a €37 million (£32.7 million) release clause inserted into his current deal with the Serie A giants, according to Italian media outlet Pagine Romaniste, and that would represent fantastic business for Liverpool, should they make a move for him.
Manolas is a wonderfully cultured defender. He is a fully accomplished passer of the football, strong in the air, and quick along the ground.
Standing at nearly 6ft 3in, the Greece international possesses the type of frame required to be a success in England, what with the robust nature of the Premier League.
He is also highly experienced in playing at the very highest level, having joined Roma from Olympiacos three years ago.
Manolas has played 140 games over the past three years - a statistic that highlights his robust nature, and that is something that is a prerequisite for any Klopp signing, what with the German's insistence on a highly intense style of play.
And if he manages to bring the Greek centre-back to Anfield, it could turn out to be a signing of real significance for Liverpool.