West Brom head into the game having drawn 1-1 at Tottenham Hotspur on Saturday afternoon, with caretaker boss Gary Megson leading his side to an impressive point.
With a point on the road after Tony Pulis' sacking, West Brom will now hope to follow that up with a home win tonight, especially against a side as beleaguered as Newcastle.
The Baggies line up with Ben Foster in goal, and a familiar back four of Allan Nyom, Ahmed Hegazi, Jonny Evans and Kieran Gibbs.
Gareth Barry partners Jake Livemore in the middle of the park, with Sam Field, Hal Robson-Kanu and Matt Phillips supporting lone striker Salomon Rondon.
Summer signigngs Jay Rodriguez and Grzegorz Krychowiak are only on the bench tonight, alongside Boaz Myhill, Claudio Yacob, James McClean, Oliver Burke and Gareth McAuley.
Meanwhile, Newcastle are in turmoil right now having suffered four straight defeats, with Saturday's 3-0 defeat to Watford adding to the losses at the hands of Burnley, Bournemouth and Manchester United.
The Magpies need to turn their fortunes around quickly to stop the slump, with manager Rafael Benitez making a host of changes this evening.
Karl Darlow is handed a shock recall between the sticks in place of Rob Elliot, with Chancel Mbemba returning in the back four alongside DeAndre Yedlin, Florian Lejeune and Ciaran Clark.
Isaac Hayden partners Mikel Merino in midfield, with Jonjo Shelvey dropped to the bench, whilst Jacob Murphy, Ayoze Perez and Matt Ritchie will support lone striker Joselu.
Javier Manquillo, Dwight Gayle and Mohamed Diame are also dropped to the bench alongside Elliot and Shelvey, with Rolando Aarons and Aleksandar Mitrovic joining them.
- Ben Foster
- Ahmed Hegazi
- Allan Nyom
- Kieran Gibbs
- Jonny Evans
- Gareth Barry
- Sam Field
- Jake Livermore
- Matt Phillips
- Hal Robson-Kanu
- Salomón Rondón
Substitutes: Boaz Myhill, Gareth McAuley, Oliver Burke, Grzegorz Krychowiak, James McClean, Claudio Yacob, Jay Rodriguez.
- Karl Darlow
- Ciaran Clark
- Florian Lejeune
- Chancel Mbemba
- DeAndre Yedlin
- Isaac Hayden
- Jacob Murphy
- Mikel Merino
- Matt Ritchie
- Ayoze Pérez
Substitutes: Robert Elliot, Javier Manquillo, Rolando Aarons, Mohamed Diamé, Jonjo Shelvey, Dwight Gayle, Aleksandar Mitrovic.