Rose was left out of Tottenham’s North London derby against Arsenal away from home at the Emirates Stadium last weekend.
The former Leeds United prospect did return to the team on Tuesday evening, playing in Tottenham’s 2-1 victory over Borussia Dortmund away from home in the Champions League.
Rose told The Telegraph that he was fuming at being left out of the game against Arsenal, and Spurs manager Pochettino has now responded to him.
Pochettino has also suggested that the 27-year-old could be left of the team this weekend.
Spurs will take on West Bromwich Albion at the Wembley Stadium in London in the Premier League on Saturday afternoon.
According to The Sun, Manchester United are interested in signing Rose from Tottenham in the January transfer window.
“Yes, maybe,” Pochettino told Yahoo! Sport regarding leaving Rose out of the team against West Brom. “We need to assess him.
“He was tired after the game in midweek. He told you that in the last 10 minutes he was tired, but that’s normal. It doesn’t concern me.
“With Danny, it’s about feeling fresh and, after his injury, it’s important that every time he’s going to play he feels fresh to give his best.
“It surprised me [when I heard he was angry last weekend] but all players are upset when they’re not involved.
"Out of 19 or 20 players, on matchday I say ‘ok that’s the starting 11, the ones on the bench’, and the two who are out of the squad, if you had a camera on their faces it would scare you.”