United will take on Liverpool away from home at Anfield in the Premier League on Saturday afternoon.
Former Arsenal defender Keown has backed the Red Devils to pick up all three points from the encounter courtesy of a 1-0 win.
“I can see Manchester United winning this 1-0,” Keown told The Daily Mail when asked for his prediction.
“These are two titanic teams with great histories but United have the momentum in this rivalry right now.”
Liverpool are seventh in the Premier League table at the moment with 12 points from seven matches.
The Merseyside outfit are just a point behind Chelsea, who are the defending champions and are currently fourth in the standings.
Jurgen Klopp’s side will head into the match against United on the back of a 1-1 draw with Newcastle United away from home at St. James’ Park in the league.
Meanwhile, the Red Devils are second in the Premier League table with 19 points from seven matches.
Jose Mourinho’s side are level on points with leaders Manchester City and will fancy their chances of winning agains Liverpool at Anfield on Saturday afternoon.