Pochettino has suggested that a proper pre-season has helped the France international perform well for Tottenham so far this season.
The Spurs manager made the comments following his side’s 4-0 victory over Huddersfield Town away from home in the Premier League on Saturday afternoon.
Sissoko did not start the encounter at the John Smith's Stadium, but the former Newcastle United midfielder came on as a substitute in the 75th minute.
The 28-year-old midfielder scored for Spurs in the first minute of injury time to wrap up a 4-0 win for the North London outfit.
“I think he's completely different today to last season,” Pochettino told Football.London about Sissoko. “He's more confident, it's a relief, but it's different to last season and that is normal.
“Last season when he arrived at the club it was without a pre-season and at the end of the transfer market. It's so difficult sometimes to settle quickly into the philosophy and expectation of the team.”
Sissoko joined Tottenham from Newcastle on transfer deadline day last summer for a fee reported by BBC Sport to be worth £30 million.
The France international struggled to make an impact at White Hart Lane last season, but he seems to have established himself as an important player in Pochettino’s team this campaign.