Tottenham Hotspur were linked with the 25-year-old back in February, and at times before that.
Isco scored twice on Saturday as Spain thrashed Italy 3-0 in World Cup qualifying.
Two excellent first-half goals from the Spaniard helped La Roja into a 2-0 lead by half time, before Alvaro Morata completed the scoring 13 minutes from the end.
Plenty of Spain fans will be loving the 25-year-old for his class, but Tottenham Hotspur supporters have been blown away by the Real Madrid man, too.
It was reported by The Mirror back in February that Tottenham boss Mauricio Pochettino would make a move for the former Malaga man this summer, which never materialised.
Isco went on to help Madrid to a second successive Champions League crown under Zinedine Zidane, starting the 4-1 demolition of the Juventus in the final.
His heroics for Spain will only cause his star to rise even further, making him less attainable for Tottenham, but their fans have reminisced about the time they were linked with him.
There was a time when Madrid were selling Isco to spurs and today he is pivotal player for Madrid and Spain,time changes too quickly-❤️— MEHRAN KHAN (@lightningMehran) September 3, 2017
To think we could have had Isco at one point...— Spurs fan (@SpursRC) September 2, 2017
Isco has been on some mad stretch of form ever since he was linked with Spurs— CHINO (@StringerFooty) September 2, 2017
Just watched Spain trash Italy 3-0. Isco is incredible, what a player. Asensio as a false nine was actually decent— OnomahIsABaller (@SpursD22) September 2, 2017
Watching Spain v Italy. If Spurs somehow would've got Isco when it was rumoured, we would've won the league. What. A. Player— Stephan (@FootballGogme) September 2, 2017
Isco is such a baller man. Jesus Christ.— Oliver (@OliSpurs) September 2, 2017
Isco, who joined los Blancos in 2013, is certainly a class act and you wonder whether he will be at the Bernabeu for a while longer. Zidane is clearly a big fan of the playmaker so it is hard to see him leaving while the Frenchman remains in charge in the Spanish capital.