Pochettino tried three different options against the Saints, none of which truly worked.
Tottenham's Harry Kane
Tottenham Hotspur beat Southampton to ensure that the gap between themselves and leaders Chelsea in the Premier League table remains at ten points.
However, the victory only papered over the cracks of a deeper issue for manager Mauricio Pochettino - how do you replace Harry Kane upfront?
Well it seems that Pochettino does not have the answer as yet.
Heung-Min Son started as the number nine against the Saints, but his lack of physical presence as the sole striker was quickly exposed by a well drilled Southampton defence.
So to plan b. Off came Son and instead Dele Alli was moved to play as a false nine. Again, though, this did not satisfy Pochettino as although Alli was on the score-sheet, his effort came from the penalty spot.
Tottenham's Harry Kane scores their second goal
Finally the Argentine tried his final option, Vincent Janssen. Unfortunately this display was no more convincing that many of the Dutchman's in what has been a difficult first year in England.
Tottenham may have won, but the Kane problem has not been solved; which is tricky when the Telegraph have reported the 23-year-old could miss six weeks through injury.