Pochettino made the admission ahead of Tottenham’s game against West Bromwich Albion in the Premier League this weekend.
Spurs will return to action on Saturday afternoon when they take on West Brom at White Hart Lane in North London.
Pochettino has admitted that it will not be easy for him to pick his starting lineup against the Baggies.
“Yes, it’s hard,” Pochettino told Tottenham’s official website when asked if picking the team will be one of his most difficult tasks as boss.
“It’s a difficult decision but we know very well the business and we all know football. When you are in a team and sign a contract you sign to train and to be ready.
“Then a club signs a manager and coach to pick 11 and seven (substitutes), decide a philosophy and a way we need to play.”
Tottenham do have a very strong squad, with some brilliant players such as Harry Kane, Christian Eriksen and Dele Alli.
It is not easy for Pochettino to pick his starting lineup, especially in the midfield department.
Spurs have won their last six matches in all competitions, scoring 17 goals and conceding just three in the process, according to BBC Sport.
The North London outfit have conceded only five league goals at home, the fewest in the division, according to BBC Sport.
Tottenham will head into the match against Tony Pulis’s side as favourites and should be able to pick up all three points with relative ease.