Second half goals from Dave Edwards and Helder Costa did the damage for Wolverhampton Wanderers, who won for the first time under Paul Lambert despite being made to fret by Joel Lynch's late consolation, which preceded nine minutes of stoppage time.
It could have been a different outcome, however, had James Perch not been sent off after collecting two yellow cards inside the opening 35 minutes.
Unsurprisingly, the versatile defender is not a popular man this morning, with many QPR fans laying the blame for last night's defeat solely with him - and who can really blame them?
If you're blaming anybody other than Perch for the reason we lost today you're clearly a melon! #QPR— Joe*QPR (@QPRJOE) 1 December 2016
Have said it time and time again, Perch is a liability. How can you jump into a challenge like that knowing you're on a yellow. #QPR— Paul Nasr (@SkyPaulNasr) 1 December 2016
James perch cost Rangers then. What's he doing diving in like that when he's on a yellow #QPR— Ricky Taylor (@QPRTaylor25) 1 December 2016
Still 5 points clear of relegation. Perch should be ashamed. Loved the guts shown the last 15, keep 11 on the field we should be fine. #QPR— Christopher Hibner (@DerbyHibby) 1 December 2016
Woeful...not really Holloway's fault, Perch being brainless has exposed the Rs inability to carefully earn a point against a poor side #QPR— Theodore (@mchaystack) 1 December 2016
#QPR won't go down so it doesn't matter too much. But this is on Perch. I'd be ashamed of that in a pub league.— Clayton Ravine (@samuelclayton) 1 December 2016
Inside Loftus Road, there were boos for another R's player, Karl Henry, upon his introduction as a second-half substitute, although most of the tweets relating to the midfielder have condemned this behaviour.
Holloway delivered an impassioned response to the Henry booing, saying as quoted by West London Sport: "You haven’t seen him play for me yet. You haven’t seen what I’m going to teach him and get him to do, so please don’t do that. I don’t like that. I don’t think that’s right.
"Yes you pay your money and you can say what you like, but I’m here to encourage people. So please don’t do that to my players.
"They’re yours too aren’t they? They might not be your favourite but please don’t do that to my players. I think I’ve got every right to say that.
"Should one of my players be booed before he’s even done anything for me? Please don’t come here with preconceived ideas. Give us a chance. It’s all I’m asking."